Andreas No Cd Patch Best ((link)): Gta San

Even the "best" patch can fail if your setup is wrong. Here is the fix list:

Mounting a disc image (virtual drive)

Using the Hoodlum exe alone is only the first step. To make the game stable on modern systems, you should pair it with: gta san andreas no cd patch best

This is widely considered the for GTA San Andreas modding and No-CD usage. Even the "best" patch can fail if your setup is wrong