You may still see YouTube tutorials or forums pointing to custom .dll files, game cracks, or "AVX2 fix" download archives.
Here are the steps to apply the fix:
AVX2 is a set of extensions to the x86 instruction set architecture that provides improved performance for floating-point and integer computations. While AVX2 is widely supported on modern CPUs, some older processors may not have full AVX2 support or may have issues with certain implementations. uncharted+4+avx2+fix+free
-skx is the magic flag. It tells the emulator to enable AVX2 and AVX-512 feature levels. -- separates the emulator command from the game command. You may still see YouTube tutorials or forums